Ioannis Sotiropoulos

Dr. Ioannis Sotiropoulos is a Researcher C – Group leader and his research work focus on understanding the orchestrating role of environmental risk factors (e.g., chronic, lifetime stress) on the onset of Alzheimer´s disease (AD) and its relationship with depression, a stress-related disorder. Combining cell-, animal- and human-based studies, Dr. Sotiropoulos’ innovative work aims to clarify the diverse factors that regulate the cellular role of Tau as a key molecule of neuroplasticity and neuropathology while his recent work focuses on exosomes as both mediators of brain pathology and potent biomarkers.

He has successfully raised funds as scientific coordinator from national and international, private and industrial sources such as FCT (Portugal), Servier (France), Jerome Leujeune Foundation (France), NIH (USA). His work is published in well-known scientific journals such as Mol Psychiatry (15), PNAS (9.7)., EMBO (9.8), Cell Death Diff (8,7), Aging Cell (6.3), J Neurosc (6). He has previously trained and worked at the Max Planck Institute of Psychiatry (Germany), Columbia University (USA), RIKEN-Brain Science Institute (Japan), University College London (UCL) & MRC Center for Synaptic Plasticity (UK), and Medical School of University of Minho (Portugal).

He has received different prizes & awards e.g., Hirnliga Alzheimer Award 2009, AD/PD Young Faculty 2014 Award, Jerome Lejeune 2017 Award, Janssen Innovation Award 2017, Alzheimer Association Award for Best Mentor in Neuroscience 2021.